Flopper.io GPU Comparison Sheet
October 25, 2026
flopper.io/compare/amd-instinct-mi250-128gb-vs-nvidia-l40s-48gbAMD Instinct MI250 128GB vs NVIDIA L40S 48GB
Side by side datacenter GPU specifications from the Flopper.io database.
Overview
| AMD Instinct MI250 128GB | NVIDIA L40S 48GB | |
|---|---|---|
| FP32 TFLOPS | 45.3 | 91.6 |
| Memory | 128 GB | 48 GB |
| Memory Bandwidth | 3.3 TB/s | 864 GB/s |
| TDP | 500 W | 350 W |
Performance by Precision
| Precision | AMD Instinct MI250 128GB peak TFLOPS (dense) | NVIDIA L40S 48GB peak TFLOPS (dense) |
|---|---|---|
| FP64 | 45.3 | 1.4 |
| FP32 | 45.3 | 91.6 |
| TF32 | — | 183.0 |
| BF16 | 362.1 | 362.1 |
| FP16 | 362.1 | 362.1 |
| FP8 | — | 733.0 |
| FP6 | — | — |
| FP4 | — | — |
| INT8 | 362.1 | 733.0 |
| INT4 | 362.1 | 733.0 |
Specifications
| AMD Instinct MI250 128GB | NVIDIA L40S 48GB | |
|---|---|---|
| Architecture | CDNA 2 | Ada Lovelace |
| Process Node | 6nm | 4nm |
| Launch Year | 2021 | 2023 |
| Form Factor | OAM | PCIe |
| Memory Type | HBM2e | — |
| Interface Width | — | — |
| Interconnect | — | — |
| TDP | 500 W | 350 W |
| FP32 Efficiency | 0.09 TFLOPS/W | 0.26 TFLOPS/W |