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AMD Instinct MI250 128GB vs AMD MI250X 128GB

The MI250X delivers 6% more FP16 throughput than the Instinct MI250 (383 vs 362 TFLOPS dense).

Instinct MI250: CDNA 2, 2021 MI250X: CDNA 2, 2021
FP16 dense lead
+6%
MI250X: 383 vs 362 TFLOPS
Memory
128 vs 128 GB
Same capacity
Bandwidth
3.3 TB/s vs 3.3 TB/s
MI250X moves data faster
TDP
500 W vs 560 W
Instinct MI250 draws 60 W less
See rental pricing from $1.28/hr Download comparison sheet

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AMD Instinct MI250 128GB vs AMD MI250X 128GB

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AMD Instinct MI250 128GB

Full specs →

What is the AMD Instinct MI250?

The Instinct MI250 is a GPU from AMD on the CDNA 2 architecture, an accelerator for AI training, inference and high-performance computing. It is an OAM module, the open accelerator format used in multi-GPU servers. Instinct MI250 full specifications →

Can I rent the Instinct MI250 in the cloud?

Yes. Cloud providers tracked by Flopper rent the Instinct MI250 by the hour, and the pricing page compares their current rates and the price history side by side. Instinct MI250 rental prices →

How does the Instinct MI250 compare with other accelerators?

This page sets the Instinct MI250 against the MI250X. Both parts launched in the same year. Both are AMD parts, and both ship as an OAM module, so they fit the same class of system. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the Instinct MI250 figures come from?

Every Instinct MI250 figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

AMD MI250X 128GB

Leads on FP16 Full specs →

What is the AMD MI250X?

The MI250X is a GPU from AMD on the CDNA 2 architecture, an accelerator for AI training, inference and high-performance computing. It is an OAM module, the open accelerator format used in multi-GPU servers. MI250X full specifications →

Can I rent the MI250X in the cloud?

Flopper is not tracking any live rental listings for the MI250X yet. The provider directory lists the clouds that rent comparable accelerators on demand. GPU cloud providers →

How does the MI250X compare with other accelerators?

This page sets the MI250X against the Instinct MI250. Both parts launched in the same year. Both are AMD parts, and both ship as an OAM module, so they fit the same class of system. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the MI250X figures come from?

Every MI250X figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

Specifications

Instinct MI250
MI250X
Architecture
CDNA 2CDNA 2
Launch Year
20212021
Form Factor
OAMOAM
Memory
128 GB128 GB
Memory Bandwidth
3.3 TB/s3.3 TB/s
TDP
500 W560 W
Process Node
6nm6nm

Performance (TFLOPS)

Instinct MI250
MI250X
45 TFLOPS 48 TFLOPS
45 TFLOPS 48 TFLOPS
No verified data available No verified data available
362 TFLOPS 383 TFLOPS
362 TFLOPS 383 TFLOPS
No verified data available No verified data available
FP6
No verified data available No verified data available
No verified data available No verified data available
362 TOPS 383 TOPS

Figures are dense. Where a vendor publishes a figure it sits under the dense one and never decides a winner. Hover any precision for its definition, or read the GPU glossary.

FLOPS by Precision

What actually differs

Both launched in 2021, the Instinct MI250 on CDNA 2 and the MI250X on CDNA 2.

Both carry 128 GB of memory. Bandwidth is 3.3 TB/s against 3.3 TB/s, which sets the ceiling on decode speed.

Power is 500 W against 560 W, and at FP32 the Instinct MI250 does more work per watt. Weight the FP8 and FP16 rows for LLM work and the FP64 row for HPC.

New to the terms? The glossary explains FP64, FP32, BF16, FP16, INT8, Sparsity and TFLOPS.

Frequently asked questions

Is the Instinct MI250 faster than the MI250X?

At FP16 precision the MI250X reaches 383 TFLOPS dense against 362 TFLOPS for the Instinct MI250. The performance table on this page lists every published precision for both GPUs.

Which should you choose, the Instinct MI250 or the MI250X?

Choose the MI250X for training and high-throughput inference: it has 6% more FP16 throughput than the Instinct MI250. The MI250X draws 60 W more power, so budget for cooling and power delivery before you commit.

Which has more memory, the Instinct MI250 or the MI250X?

Both GPUs carry 128 GB of memory. Memory bandwidth is 3.3 TB/s for the Instinct MI250 and 3.3 TB/s for the MI250X.

How much power do the Instinct MI250 and the MI250X draw?

The Instinct MI250 is rated at 500 W TDP and the MI250X at 560 W. On FP32 throughput per watt, the Instinct MI250 is the more efficient part.

How much do the Instinct MI250 and the MI250X cost to rent?

Live cloud listings tracked by Flopper price the Instinct MI250 from $1.28 per GPU-hour across 1 provider, and no live listings yet for the MI250X. The rental section on this page links to every provider, rate and the price history for each GPU.

Where to Rent

AMD Instinct MI250 128GB

Rent from

$1.28 / GPU-hr

Lowest of 4 live listings across 1 provider

See all Instinct MI250 rental prices →

Price history and every provider on the pricing page. Some links are affiliate links.

AMD MI250X 128GB

No live rental listings tracked for the MI250X yet.

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