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AMD Instinct MI100 32GB vs AMD Instinct MI250 128GB

The Instinct MI250 delivers 96% more FP16 throughput than the Instinct MI100 (362 vs 185 TFLOPS dense). The Instinct MI250 also carries 96 GB more memory (128 GB vs 32 GB).

Instinct MI100: CDNA, 2020 Instinct MI250: CDNA 2, 2021
FP16 dense lead
+96%
Instinct MI250: 362 vs 185 TFLOPS
Memory
32 vs 128 GB
96 GB more for the Instinct MI250
Bandwidth
1.2 TB/s vs 3.3 TB/s
Instinct MI250 moves data faster
TDP
300 W vs 500 W
Instinct MI100 draws 200 W less
See rental pricing from $1.28/hr Download comparison sheet

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AMD Instinct MI100 32GB vs AMD Instinct MI250 128GB

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AMD Instinct MI100 32GB

Full specs →

What is the AMD Instinct MI100?

The Instinct MI100 is a GPU from AMD on the CDNA architecture, an accelerator for AI training, inference and high-performance computing. It is a PCIe add-in card, so it fits standard servers and workstations. Instinct MI100 full specifications →

Can I rent the Instinct MI100 in the cloud?

Flopper is not tracking any live rental listings for the Instinct MI100 yet. The provider directory lists the clouds that rent comparable accelerators on demand. GPU cloud providers →

How does the Instinct MI100 compare with other accelerators?

This page sets the Instinct MI100 against the Instinct MI250. The Instinct MI100 is the older generation of the two. Both are AMD parts; the Instinct MI100 is a PCIe card while the Instinct MI250 is an OAM module. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the Instinct MI100 figures come from?

Every Instinct MI100 figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

AMD Instinct MI250 128GB

Leads on FP16 Full specs →

What is the AMD Instinct MI250?

The Instinct MI250 is a GPU from AMD on the CDNA 2 architecture, an accelerator for AI training, inference and high-performance computing. It is an OAM module, the open accelerator format used in multi-GPU servers. Instinct MI250 full specifications →

Can I rent the Instinct MI250 in the cloud?

Yes. Cloud providers tracked by Flopper rent the Instinct MI250 by the hour, and the pricing page compares their current rates and the price history side by side. Instinct MI250 rental prices →

How does the Instinct MI250 compare with other accelerators?

This page sets the Instinct MI250 against the Instinct MI100. The Instinct MI250 is the newer generation of the two. Both are AMD parts; the Instinct MI250 is an OAM module while the Instinct MI100 is a PCIe card. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the Instinct MI250 figures come from?

Every Instinct MI250 figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

Specifications

Instinct MI100
Instinct MI250
Architecture
CDNACDNA 2
Launch Year
20202021
Form Factor
PCIeOAM
Memory
32 GB128 GB
Memory Bandwidth
1.2 TB/s3.3 TB/s
TDP
300 W500 W
Process Node
7nm6nm

Performance (TFLOPS)

Instinct MI100
Instinct MI250
12 TFLOPS 45 TFLOPS
23 TFLOPS 45 TFLOPS
No verified data available No verified data available
92 TFLOPS 362 TFLOPS
185 TFLOPS 362 TFLOPS
No verified data available No verified data available
FP6
No verified data available No verified data available
No verified data available No verified data available
185 TOPS 362 TOPS

Figures are dense. Where a vendor publishes a figure it sits under the dense one and never decides a winner. Hover any precision for its definition, or read the GPU glossary.

FLOPS by Precision

What actually differs

The Instinct MI250 is the newer part: CDNA 2 (2021) against the Instinct MI100's CDNA (2020).

The Instinct MI250 carries 96 GB more memory (128 GB against 32 GB), so larger models fit on one GPU before you shard. Bandwidth is 1.2 TB/s against 3.3 TB/s, which sets the ceiling on decode speed.

Power is 300 W against 500 W, and at FP32 the Instinct MI250 does more work per watt. Weight the FP8 and FP16 rows for LLM work and the FP64 row for HPC.

New to the terms? The glossary explains FP64, FP32, BF16, FP16, INT8, Sparsity and TFLOPS.

Frequently asked questions

What is better, the Instinct MI100 or the Instinct MI250?

The Instinct MI250, on throughput. At FP16 precision the Instinct MI250 reaches 362 TFLOPS dense against 185 TFLOPS for the Instinct MI100. The performance table on this page lists every published precision for both GPUs.

Which should you choose, the Instinct MI100 or the Instinct MI250?

Choose the Instinct MI250 for training and high-throughput inference: it has 96% more FP16 throughput than the Instinct MI100. It also carries 96 GB more memory, so larger models fit on one GPU before you shard. The Instinct MI250 draws 200 W more power, so budget for cooling and power delivery before you commit. Packaging differs too: the Instinct MI100 is a PCIe card while the Instinct MI250 is an OAM module, so check what your servers accept.

Which has more memory, the Instinct MI100 or the Instinct MI250?

The Instinct MI250 carries 128 GB of memory versus 32 GB for the Instinct MI100. Memory bandwidth is 1.2 TB/s for the Instinct MI100 and 3.3 TB/s for the Instinct MI250.

How much power do the Instinct MI100 and the Instinct MI250 draw?

The Instinct MI100 is rated at 300 W TDP and the Instinct MI250 at 500 W. On FP32 throughput per watt, the Instinct MI250 is the more efficient part.

How much do the Instinct MI100 and the Instinct MI250 cost to rent?

Live cloud listings tracked by Flopper price no live listings yet for the Instinct MI100, and the Instinct MI250 from $1.28 per GPU-hour across 1 provider. The rental section on this page links to every provider, rate and the price history for each GPU.

Where to Rent

AMD Instinct MI100 32GB

No live rental listings tracked for the Instinct MI100 yet.

Browse GPU cloud providers

AMD Instinct MI250 128GB

Rent from

$1.28 / GPU-hr

Lowest of 4 live listings across 1 provider

See all Instinct MI250 rental prices →

Price history and every provider on the pricing page. Some links are affiliate links.

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