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AMD Instinct MI100 32GB vs AMD Radeon AI PRO R9600D 32GB

The Instinct MI100 delivers 86% more FP16 throughput than the Radeon AI PRO R9600D (185 vs 99 TFLOPS dense).

Instinct MI100: CDNA, 2020 Radeon AI PRO R9600D: RDNA 4, 2025
FP16 dense lead
+86%
Instinct MI100: 185 vs 99 TFLOPS
Memory
32 vs 32 GB
Same capacity
Bandwidth
1.2 TB/s vs 640 GB/s
Instinct MI100 moves data faster
TDP
300 W vs 150 W
Radeon AI PRO R9600D draws 150 W less
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AMD Instinct MI100 32GB vs AMD Radeon AI PRO R9600D 32GB

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AMD Instinct MI100 32GB

Leads on FP16 Full specs →

What is the AMD Instinct MI100?

The Instinct MI100 is a GPU from AMD on the CDNA architecture, an accelerator for AI training, inference and high-performance computing. It is a PCIe add-in card, so it fits standard servers and workstations. Instinct MI100 full specifications →

Can I rent the Instinct MI100 in the cloud?

Flopper is not tracking any live rental listings for the Instinct MI100 yet. The provider directory lists the clouds that rent comparable accelerators on demand. GPU cloud providers →

How does the Instinct MI100 compare with other accelerators?

This page sets the Instinct MI100 against the Radeon AI PRO R9600D. The Instinct MI100 is the older generation of the two. Both are AMD parts, and both ship as a PCIe card, so they fit the same class of system. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the Instinct MI100 figures come from?

Every Instinct MI100 figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

AMD Radeon AI PRO R9600D 32GB

Full specs →

What is the AMD Radeon AI PRO R9600D?

The Radeon AI PRO R9600D is a GPU from AMD on the RDNA 4 architecture, an accelerator for AI training, inference and high-performance computing. It is a PCIe add-in card, so it fits standard servers and workstations. Radeon AI PRO R9600D full specifications →

Can I rent the Radeon AI PRO R9600D in the cloud?

Flopper is not tracking any live rental listings for the Radeon AI PRO R9600D yet. The provider directory lists the clouds that rent comparable accelerators on demand. GPU cloud providers →

How does the Radeon AI PRO R9600D compare with other accelerators?

This page sets the Radeon AI PRO R9600D against the Instinct MI100. The Radeon AI PRO R9600D is the newer generation of the two. Both are AMD parts, and both ship as a PCIe card, so they fit the same class of system. The compare tool builds the same comparison for any two parts in the catalogue. All GPU comparisons →

Where do the Radeon AI PRO R9600D figures come from?

Every Radeon AI PRO R9600D figure on this page traces to AMD's own datasheet or specification table. How Flopper verifies specifications →

Specifications

Instinct MI100
Radeon AI PRO R9600D
Architecture
CDNARDNA 4
Launch Year
20202025
Form Factor
PCIePCIe
Memory
32 GB32 GB
Memory Bandwidth
1.2 TB/s640 GB/s
TDP
300 W150 W
Process Node
7nm—

Performance (TFLOPS)

Instinct MI100
Radeon AI PRO R9600D
12 TFLOPS No verified data available
23 TFLOPS 25 TFLOPS
No verified data available No verified data available
92 TFLOPS No verified data available
185 TFLOPS 99 TFLOPS
199 TFLOPS sparse
No verified data available199 TFLOPS
397 TFLOPS sparse
FP6
No verified data available No verified data available
No verified data available No verified data available
185 TOPS 199 TOPS
397 TOPS sparse

Figures are dense. Where a vendor publishes a figure it sits under the dense one and never decides a winner. Hover any precision for its definition, or read the GPU glossary.

FLOPS by Precision

What actually differs

The Radeon AI PRO R9600D is the newer part: RDNA 4 (2025) against the Instinct MI100's CDNA (2020).

Both carry 32 GB of memory. Bandwidth is 1.2 TB/s against 640 GB/s, which sets the ceiling on decode speed.

Power is 300 W against 150 W, and at FP32 the Radeon AI PRO R9600D does more work per watt. Weight the FP8 and FP16 rows for LLM work and the FP64 row for HPC.

New to the terms? The glossary explains FP64, FP32, BF16, FP16, FP8, INT8, Sparsity and TFLOPS.

Frequently asked questions

What is better, the Instinct MI100 or the Radeon AI PRO R9600D?

The Instinct MI100, on throughput. At FP16 precision the Instinct MI100 reaches 185 TFLOPS dense against 99 TFLOPS for the Radeon AI PRO R9600D. The performance table on this page lists every published precision for both GPUs.

Which should you choose, the Instinct MI100 or the Radeon AI PRO R9600D?

Choose the Instinct MI100 for training and high-throughput inference: it has 86% more FP16 throughput than the Radeon AI PRO R9600D. The Instinct MI100 draws 150 W more power, so budget for cooling and power delivery before you commit.

Which has more memory, the Instinct MI100 or the Radeon AI PRO R9600D?

Both GPUs carry 32 GB of memory. Memory bandwidth is 1.2 TB/s for the Instinct MI100 and 640 GB/s for the Radeon AI PRO R9600D.

How much power do the Instinct MI100 and the Radeon AI PRO R9600D draw?

The Instinct MI100 is rated at 300 W TDP and the Radeon AI PRO R9600D at 150 W. On FP32 throughput per watt, the Radeon AI PRO R9600D is the more efficient part.

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