AMD Instinct MI210 PCIe vs AMD Instinct MI250 128GB
The Instinct MI250 delivers 2.0x the FP16 throughput of the Instinct MI210 (362 vs 181 TFLOPS dense). The Instinct MI250 also carries 64 GB more memory (128 GB vs 64 GB).
AMD Instinct MI210 PCIe
Full specs →AMD Instinct MI250 128GB
Full specs →Specifications
Performance (TFLOPS)
FLOPS by Precision
What actually differs
The Instinct MI210 is the newer part: CDNA 2, launched in 2022, against the Instinct MI250's CDNA 2 from 2021. Newer architectures typically add lower-precision formats and better throughput per watt, so check the precision rows your workload actually uses.
Dense throughput for the Instinct MI210 against the Instinct MI250: FP64 23 vs 45 TFLOPS, FP32 23 vs 45 TFLOPS, FP16 181 vs 362 TFLOPS. Sparse figures, where the vendor publishes them, appear under each dense number in the performance table.
Memory is 64 GB against 128 GB, fed at 1.6 TB/s versus 3.3 TB/s. More memory per GPU means larger models fit before you have to shard across cards, which often matters more than raw TFLOPS for inference.
Power budgets are 300 W for the Instinct MI210 and 500 W for the Instinct MI250. At FP32 that works out to 0.08 against 0.09 TFLOPS per watt.
For LLM training and inference, weight the FP8 and FP16 rows and memory capacity most heavily. For scientific and HPC workloads, the FP64 row is the one to read.
Frequently asked questions
Is the Instinct MI210 faster than the Instinct MI250?
At FP16 precision the Instinct MI250 reaches 362 TFLOPS dense against 181 TFLOPS for the Instinct MI210. The performance table on this page lists every published precision for both GPUs.
Which has more memory, the Instinct MI210 or the Instinct MI250?
The Instinct MI250 carries 128 GB of VRAM versus 64 GB for the Instinct MI210. Memory bandwidth is 1.6 TB/s for the Instinct MI210 and 3.3 TB/s for the Instinct MI250.
How much power do the Instinct MI210 and the Instinct MI250 draw?
The Instinct MI210 is rated at 300 W TDP and the Instinct MI250 at 500 W. On FP32 throughput per watt, the Instinct MI250 is the more efficient part.
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