AMD Instinct MI210 PCIe vs AMD MI250X 128GB
The MI250X delivers 2.1x the FP16 throughput of the Instinct MI210 (383 vs 181 TFLOPS dense). The MI250X also carries 64 GB more memory (128 GB vs 64 GB).
AMD Instinct MI210 PCIe
Full specs →AMD MI250X 128GB
Full specs →Specifications
Performance (TFLOPS)
FLOPS by Precision
What actually differs
The Instinct MI210 is the newer part: CDNA 2, launched in 2022, against the MI250X's CDNA 2 from 2021. Newer architectures typically add lower-precision formats and better throughput per watt, so check the precision rows your workload actually uses.
Dense throughput for the Instinct MI210 against the MI250X: FP64 23 vs 48 TFLOPS, FP32 23 vs 48 TFLOPS, FP16 181 vs 383 TFLOPS. Sparse figures, where the vendor publishes them, appear under each dense number in the performance table.
Memory is 64 GB against 128 GB, fed at 1.6 TB/s versus 3.3 TB/s. More memory per GPU means larger models fit before you have to shard across cards, which often matters more than raw TFLOPS for inference.
Power budgets are 300 W for the Instinct MI210 and 560 W for the MI250X. At FP32 that works out to 0.08 against 0.09 TFLOPS per watt.
For LLM training and inference, weight the FP8 and FP16 rows and memory capacity most heavily. For scientific and HPC workloads, the FP64 row is the one to read.
Frequently asked questions
Is the Instinct MI210 faster than the MI250X?
At FP16 precision the MI250X reaches 383 TFLOPS dense against 181 TFLOPS for the Instinct MI210. The performance table on this page lists every published precision for both GPUs.
Which has more memory, the Instinct MI210 or the MI250X?
The MI250X carries 128 GB of VRAM versus 64 GB for the Instinct MI210. Memory bandwidth is 1.6 TB/s for the Instinct MI210 and 3.3 TB/s for the MI250X.
How much power do the Instinct MI210 and the MI250X draw?
The Instinct MI210 is rated at 300 W TDP and the MI250X at 560 W. On FP32 throughput per watt, the MI250X is the more efficient part.
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