Alibaba Qwen3.5

Qwen3.5-397B-A17B hardware requirements

Needs at least 4 GPUs at BF16 (Instinct MI350X OAM). For 1,000 tokens/s at 32k context you need 16 x H100 SXM5 80GB at $28.64/hr or 16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition at $8.00/hr.

Parameters
403B
Active per token
17.0B
mixture of experts
KV cache per token
30 KB
16-bit cache
Native precision
BF16

Bare minimum

Fewest GPUs
4 x Instinct MI350X OAM
BF16, 4,096 tokens, one stream
Tokens/s
629
Per hour
$24.64
Per million tokens
$10.87
Memory used
73%
Rent on DigitalOcean
Cheapest per hour
16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition
BF16, 4,096 tokens, one stream, live price
Tokens/s
470
Per hour
$8.00
Per million tokens
$4.73
Memory used
55%
Rent on RunPod
Cheapest per million tokens
16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition
BF16, 32,768 tokens, 32 streams
Tokens/s
7.1k
Per hour
$8.00
Per million tokens
$0.31
Memory used
58%
Rent on RunPod

Configurations

Every datacenter GPU in the catalog, sized for these settings. Change precision, context and concurrency and the whole page follows. Each point is one replica: the smallest tensor-parallel group of that GPU that holds the model.

Vendor

4 x GB300 NVL72 GPU 288GB: 9.6k tokens/s per replica at $34.48/hr.8 x GB200 NVL72 GPU 186GB: 18k tokens/s per replica at $84.00/hr.4 x Instinct MI350X OAM: 9.6k tokens/s per replica at $24.64/hr.4 x B300 SXM 262GB: 9.6k tokens/s per replica at $29.60/hr.8 x B200 SXM 180GB: 17k tokens/s per replica at $32.72/hr.4 x Instinct MI325X OAM: 7.2k tokens/s per replica at $15.20/hr.8 x Instinct MI300X 192GB: 12k tokens/s per replica at $19.12/hr.8 x H200 SXM 141GB: 11k tokens/s per replica at $23.92/hr.16 x H100 SXM5 80GB: 13k tokens/s per replica at $28.64/hr.8 x H200 NVL 141GB: 11k tokens/s per replica at $30.32/hr.16 x H100 NVL 94GB: 16k tokens/s per replica at $51.04/hr.16 x H100 PCIe 80GB: 8.0k tokens/s per replica at $40.00/hr.16 x RTX PRO 6000 Blackwell Workstation Edition: 7.1k tokens/s per replica at $28.80/hr.16 x RTX PRO 6000 Blackwell Server Edition: 6.4k tokens/s per replica at $9.44/hr.16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition: 7.1k tokens/s per replica at $8.00/hr.16 x A100 PCIe 80GB: 7.7k tokens/s per replica at $21.60/hr.16 x A100 SXM4 80GB: 8.1k tokens/s per replica at $22.40/hr.

Priced configurations only; 14 more fit without a live price and appear in the table. Marker size grows with the tensor-parallel width. Roofline estimates.

GPUTPTokens/s
4 ~28k Specs
4 26k Specs
4 9.6k Specs
4 9.6k Rent
8 18k Rent
4 9.6k Rent
4 9.6k Rent
8 17k Rent
8 18k Specs
4 7.2k Rent
8 12k Rent
Biren logo
BR100 2 nodes
16 6.4k Specs
8 11k Rent
16 13k Rent
8 7.4k Specs
8 ~11k Rent
H100 NVL 94GB 2 nodes
16 ~16k Rent
16 8.0k Rent
16 8.0k Specs
16 7.1k Rent
16 ~6.4k Rent
16 7.1k Rent
8 7.4k Specs
8 7.4k Specs
16 7.7k Specs
16 7.7k Rent
16 8.1k Rent
16 ~5.4k Specs
16 6.5k Specs
8 9.0k Specs
H20 96GB 2 nodes
16 16k Specs

AMD vs NVIDIA

At BF16 the NVIDIA pick is 16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition at about 7.1k tokens/s for $8.00/hr; the AMD pick is 8 x Instinct MI300X 192GB at about 12k tokens/s for $19.12/hr. Per rental dollar NVIDIA delivers 1.43x the tokens of AMD here.

NVIDIA: 893 tokens/s per dollar, 1.5k tokens/s per kW (16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition).AMD: 626 tokens/s per dollar, 2.0k tokens/s per kW (8 x Instinct MI300X 192GB).Intel: no live price, 1.5k tokens/s per kW (8 x Data Center GPU Max 1550 128GB).Other: no live price, 725 tokens/s per kW (16 x BR100).

NVIDIA 21 parts fit
Best value: 16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition, 7.1k tok/s for $8.00/hr
Fewest GPUs: 4 x Rubin SXM, 26k tok/s
AMD 8 parts fit
Best value: 8 x Instinct MI300X 192GB, 12k tok/s for $19.12/hr
Fewest GPUs: 4 x Instinct MI455X OAM, 28k tok/s
Intel 1 parts fit
Fewest GPUs: 8 x Data Center GPU Max 1550 128GB, 7.4k tok/s
Other 1 parts fit
Fewest GPUs: 16 x BR100, 6.4k tok/s

Fleet what-if

Compare whole fleets at these settings: a thousand of one part against a hundred of another. Each fleet splits into replicas of its tensor-parallel width; GPUs left over sit idle.

A
B
FleetReplicasTokens/s
A 1,000 x H200 SXM 141GB 125 x TP8 1.36M
B 104 x GB200 NVL72 GPU 186GB 13 x TP8 235k

1,000 x H200 SXM 141GB: 1.36M tokens/s, $2,990/hr, 700 kW.104 x GB200 NVL72 GPU 186GB: 235k tokens/s, $1,092/hr, no power figure.

H200 SXM 141GB: 1.36M tokens/s at 1000 GPUs.GB200 NVL72 GPU 186GB: 2.26M tokens/s at 1000 GPUs.

Size Qwen3.5-397B-A17B for a tokens per second target

The calculator starts from your traffic instead of a fleet: set a target rate and read the replica count for every GPU.

Frequently asked questions

How much GPU memory does Qwen3.5-397B-A17B need?

The weights take 807 GB at the native BF16 precision (807 GB at BF16, 403 GB at FP8, 227 GB at INT4). Each concurrent stream adds 30 KB of KV cache per token: 0.1 GB at 4,096 tokens and 1.0 GB at 32,768 tokens.

What is the bare minimum to run Qwen3.5-397B-A17B?

4 x Instinct MI350X OAM at BF16 with 4,096 tokens of context and one stream. The cheapest live rental for that footprint is 16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition at $8.00 per hour.

How many H100s do you need to run Qwen3.5-397B-A17B?

16 H100s at BF16 for 4,096 tokens of context and one stream. For 32,768 tokens and 32 concurrent streams the tensor-parallel group is 16 H100s, and 1,000 tokens per second takes 16 H100s across 1 replicas.

How much does Qwen3.5-397B-A17B cost per million tokens on an H100?

About $0.60 per million output tokens at BF16, 32,768 tokens of context and 32 streams, using the cheapest live on-demand price of $1.79 per GPU-hour. The cheapest part per token is 16 x RTX PRO 6000 Blackwell Max-Q Workstation Edition at $0.31.

What precision does Qwen3.5-397B-A17B ship in?

The published checkpoint is BF16. FP8 and INT4 figures describe post-training quantisations that halve and quarter the footprint at a small accuracy cost.

All figures are roofline estimates from the model's config.json and each GPU's published memory, bandwidth and tensor-core peak, with fixed efficiency factors. Prices are the cheapest live on-demand listing per GPU when the site has one. They are a planning floor; a tuned serving stack can do better. Only the 15 full-attention layers keep a per-token cache. The 45 linear-attention layers hold a fixed 189 MB state per sequence (64 value heads x 128 x 128 in FP32 per layer).